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Nature's Health Choles-Balance contains red yeast rice, an exclusive source of standardized Monascus purpureus yeast (or Red Yeast) fermented on premium rice, which naturally contains HMG-CoA reductase inhibitors (>0.5%) and major unsaturated fatty acids (0.8-2%) which are extremely effective in reducing elevated serum cholesterol and triglycerides in the blood. This product can be used to suppress atherosclerosis and hyperlipidemia and to prevent the occurrence of heart disease, diabetes, high blood pressure and obesity. A clinical trial was inducted by several hospitals affiliated with the Chinese FDA (The Bureau of Drug Administration, Ministry of Public Health of China) in the early 1990. A total of 446 patients with hyperlipidemia were randomly assigned to two groups in the trial (see table below, ref. 1).

Summary of Results of Multi-Center Clinical Trial
on the Serum Lipid-Lowing Effects of Red Yeast Rice

Measurement

Red Yeast Rice Treated**

Control Group*

Numbers of patients

324

122

Decrease in Total Cholesterol

-22.7%

-7.0%

Decrease in LDL (bad)

-30.9%

-8.3%

Increase in HDL (good)

+19.9%

+8.4%

Decrease in Triglycerides

-34.1%

-12.8%

Total Benefic (est. by MPH of China)

93.2%

50.8%

*The poditive Control Group was given Chinese herbal medicine, Jiaogulan (Gynostemma pentaphylla).
**The Study group was given M. purpureus (red yeast) rice preparations.

Our lab conducted an acute toxicity study of Red Yeast on mice. It showed that the maximum tolerant dose in mice is greater than 13g/kg, which is almost 150 times the daily dosage. A long term toxicity study on rats demonstrated no significant difference in behavior, dieting, feces, urine, color of hair, or weight after 2 months and 4 months of forced feeding of Red Yeast (ref. 2).

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